Hello Heather,
Welcome and wish it could be on a more positive note.
You asked for some guidance and my first thought is maybe you should seek out one-on-one counseling for your depression/anxiety disorder. If not, do you have a mentor where you work that you can seek out? Nurses need to acquire a tough exterior. Patient's and their family members are scared of the unknown. They rarely see the MD's. So, they will reach out to the nursing staff with questions that the MD's may not even be able to answer. Most people are at their worse when they are in the hospital, both as patients & family members. Most of the the time this transference is not meant as a personal hit against a nurse.
You may need to consider toughening up your soft personality so that your feelings are not easily offended. The nursing profession is often a thankless job, especially for those that work the night shift. Maybe you are not meant to work the night shift. Furthermore, I worked the night shift on a Tele Ward, then went on to work in an ICU at a different hospital. You have worked almost year and a half on Med-Surg Tele and maybe your more ready than you think to move on to an ICU position?
Finally, do you have any hobbys or special interest outside of nursing? We all need outlets that allow us to let go of the stress of nursing when not at work?