Results 1 to 3 of 3

Thread: New iron drug improves anemia with kidney disease

  1. #1
    Super Moderator cougarnurse's Avatar
    Join Date
    Oct 2006
    Location
    Parked in front of the computer when I am not working
    Posts
    12,364

    New iron drug improves anemia with kidney disease

    Anyone see this used in their practice yet? MedlinePlus: New iron drug improves anemia with kidney disease

    NEW YORK (Reuters Health) - Treatment with ferumoxytol, a new iron drug that is given intravenously, is more effective against anemia than standard iron therapy, which is given by mouth, in patients with chronic kidney disease, results of a new study indicate.
    Anemia, which typically involves symptoms of fatigue and weakness, is common in patients with chronic kidney disease and usually relates to decreased production of a chemical that stimulates the production of red blood cells. In some patients, however, low iron levels may be a contributing factor.
    In the present study, Dr. Annamaria Krausz, at Tufts-New England Medical Center in Boston, and colleagues assessed the outcomes of 304 patients with kidney disease and anemia who were randomly assigned to receive two ferumoxytol doses given within 1 week or daily oral iron therapy for 21 days. About 40 percent of the subjects were also taking drugs designed to stimulate red blood cell production.
    Compared with oral iron therapy, treatment with ferumoxytol produced a greater increase in blood levels of hemoglobin, indicating that the drug was more effective in treating anemia. Moreover, ferumoxytol was well tolerated and less likely to cause side effects than oral iron therapy.
    Given its effectiveness, ferumoxytol may help patients reduce their dosage of red blood cell-stimulating drugs or avoid these agents all together.
    The study findings will appear in an upcoming issue of the Journal of the American Society of Nephrology.
    According to a press statement, AMAG Pharmaceuticals has submitted these trial results to the US Food and Drug Administration as part of a New Drug Application seeking marketing approval for ferumoxytol to treat iron deficiency anemia in patients with chronic kidney disease.
    SOURCE: Journal of the American Society of Nephrology, August 2008.

  2. #2
    Senior Member
    Join Date
    Apr 2007
    Posts
    102

    Re: New iron drug improves anemia with kidney disease

    Quote Originally Posted by cougarnurse View Post
    Anyone see this used in their practice yet? MedlinePlus: New iron drug improves anemia with kidney disease

    NEW YORK (Reuters Health) - Treatment with ferumoxytol, a new iron drug that is given intravenously, is more effective against anemia than standard iron therapy, which is given by mouth, in patients with chronic kidney disease, results of a new study indicate.
    Anemia, which typically involves symptoms of fatigue and weakness, is common in patients with chronic kidney disease and usually relates to decreased production of a chemical that stimulates the production of red blood cells. In some patients, however, low iron levels may be a contributing factor.
    In the present study, Dr. Annamaria Krausz, at Tufts-New England Medical Center in Boston, and colleagues assessed the outcomes of 304 patients with kidney disease and anemia who were randomly assigned to receive two ferumoxytol doses given within 1 week or daily oral iron therapy for 21 days. About 40 percent of the subjects were also taking drugs designed to stimulate red blood cell production.
    Compared with oral iron therapy, treatment with ferumoxytol produced a greater increase in blood levels of hemoglobin, indicating that the drug was more effective in treating anemia. Moreover, ferumoxytol was well tolerated and less likely to cause side effects than oral iron therapy.
    Given its effectiveness, ferumoxytol may help patients reduce their dosage of red blood cell-stimulating drugs or avoid these agents all together.
    The study findings will appear in an upcoming issue of the Journal of the American Society of Nephrology.
    According to a press statement, AMAG Pharmaceuticals has submitted these trial results to the US Food and Drug Administration as part of a New Drug Application seeking marketing approval for ferumoxytol to treat iron deficiency anemia in patients with chronic kidney disease.
    SOURCE: Journal of the American Society of Nephrology, August 2008.
    I've been in HD since the late 80's. We've been telling dialysis patients not to take oral iron ever since I started HD. Nothing new to that. They can't metabolize oral iron. We started with Infed, went to Ferrlicet, and now Venofer.
    The "chemical" ESRD patients lack is a hormone secreted by the kidneys that tells the bone marrow to produce red blood cells.

    Venofer has been given for >30 years without any deaths associated with it. A safe drug. Works well, doesn't need to be held for monthly labs, proven effective in helping lower Epogen doses. No test dose needed.

    No need for a new drug.

  3. #3
    Junior Member
    Join Date
    Jan 2009
    Posts
    1
    What is its exact effect on Anemia Disease?

Similar Threads

  1. Study: stroke risk with anemia drug Aranesp
    By cougarnurse in forum Medication Discussion, Education, and News
    Replies: 0
    Last Post: 11-01-2009, 01:48 PM
  2. Anemia of Chronic Renal Failure
    By cougarnurse in forum Dialysis-Renal-Nephrology Nursing
    Replies: 0
    Last Post: 08-01-2009, 11:35 AM
  3. New iron drug improves anemia with kidney disease
    By cougarnurse in forum Medication Discussion, Education, and News
    Replies: 0
    Last Post: 07-01-2008, 09:15 PM
  4. Iron sharpening iron
    By The unexplainable Moo Cow in forum General Nursing Discussion
    Replies: 1
    Last Post: 11-05-2006, 04:05 PM
  5. Hospitalized hunter's condition improves
    By nursebot in forum Nursing News
    Replies: 0
    Last Post: 09-06-2006, 11:59 AM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •